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The clinical manifestations of POI are elevated gonadotropins, decline in estrogen, menstrual disorders and infertility

J Funct Foods 66:103832 Ianni F, Blasi F, Angelini P, Simone SCD, Angeles Flores G, Cossignani L, Venanzoni R (2021) Extraction optimization by experimental design of bioactives from Pleurotus ostreatus and evaluation of antioxidant and antimicrobial activities

They are getting a different, less effective one

He takes patients through the following steps: situational analysis, perception of the disease, acceptance of the syndrome, life balance of those affected, and finally, ways to live a more integrated life